By Eleanor Garth – Longevity.Technology –
New research reveals senescence is not a single process but a spectrum of cellular states with implications for precision longevity therapies.
The accumulation of senescent cells is increasingly seen as a major contributor to aging and age-related diseases. These senescent cells – often referred to as “zombie cells” because they cease dividing but refuse to die – build up in tissues over time, secreting inflammatory and tissue-damaging factors. Their presence has been linked to chronic diseases such as osteoarthritis, cardiovascular disease and neurodegeneration. A growing field of research has sought ways to eliminate these cells, and while functional differences have been observed across tissues, senescence within a given cell type has often been treated as uniform.
