By Emily Mullin – Wired

The FDA has yet to approve any drugs for life extension. But biotech company Loyal is now a step closer to bringing one to market—for dogs.

There’s a well-established inverse relationship between a dog’s size and its expected lifespan. Bernese mountain dogs and Great Danes live just six to eight years, for example, while corgis can live up to 15 years and Chihuahuas up to two decades.

San Francisco biotech company Loyal wants to close that gap, and is developing an experimental drug to extend the lifespan and improve the quality of life of large and giant dog breeds. Today, the company announced that based on early data, the US Food and Drug Administration has determined that Loyal’s drug has a “reasonable expectation of effectiveness.” The company hasn’t yet shown that its drug actually extends lifespan, but the FDA decision signals the agency’s confidence in Loyal’s approach, and the drug will soon be tested in a bigger trial.

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