It’s time to cure #Parkinsons NOW! The passage of two California ballot measures- Prop 71 and Prop 14- authorized $8.5 billion for #stemcellresearch & established the independent California Institute for Regenerative Medicine #CIRM. That State Agency is like a CA. mini-NIH for regenerative medicine- unique in the entire country. I was so very happy to serve on the governing board of the 2020 ballot campaign- and hugely relieved that the voters passed the initiative! The Agency’s investing $4 million in a late-stage preclinical project by #RyneBio aiming to improve treatment for Idiopathic Parkinson’s disease- a devastating affliction. Loss of #dopamine producing neurons that result in motor symptoms, such as #dyskinesias & non-motor effects such as #dementia, #depression & #sleepdisorders – impacting about 1 million people in the US. This project aims at restoring #dopamineneurons. The grant funds a #IND enabling nonclinical safety studies. CIRM has invested more than $59 million in helping research for PD- from a basic discovery level through #clinicaltrials.

-Bernard Siegel

 

by Esteban Cortez – The Stem Cellar (CIRM)

The California Institute for Regenerative Medicine (CIRM) is investing $4 million in a late-stage preclinical project by Ryne Bio aiming to improve treatment for Idiopathic Parkinson’s disease (PD).

PD is characterized by a loss of dopamine producing neurons that result in motor symptoms, such as dyskinesias (involuntary, erratic, writhing movements of the face, arms, legs or trunk) and non-motor effects such as dementia, depression and sleep disorders.

PD is the second-most common neurodegenerative disease after Alzheimer’s disease affecting approximately 1 million people in the U.S. In California, it is estimated that 116,900 people live with PD, representing the highest number of people with the disease in the country.

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