By Josh Conway – Lifespan.io
A review paper published in Cells has described multiple ways in which the secretion of extracellular vesicles (EVs) changes with aging, leading the authors to propose it as its own hallmark.
Extracellular vesicles and their uses
This review begins with an outline and explanation of extracellular vesicles and their classifications. Cells use extracellular vesicles to signal to one another [1]. Exosomes form from endosomes that are gathered into multivescular bodies, microvesicles are sent directly from the plasma membrane, and apoptotic bodies are the final messages sent by cells undergoing programmed death by apoptosis [2].
