by Josh Conway – Lifespan.io –
Researchers have discovered a cocktail of micro-RNA strands that make some extracellular vesicles (EVs) effective in reducing cellular senescence and published their findings in Aging Cell.
The researchers began their paper discussing the well-trodden ground of senolytics, which kill senescent cells, and senomorphics, which alter them instead. They noted that cellular senescence is often targeted in aging because it is presumably easier to drug than other aspects are, and they listed various senolytics and senomorphics, such as fisetin and the well-known combination of dasatinib and quercetin. They even noted rapamycin’s senomorphic qualities
