By Neuroscience News –
A new study reveals that immune resilience, a person’s ability to maintain a robust, youthful immune system, plays a critical role in promoting long-term health and extending life. By analyzing data from over 17,000 individuals, researchers found that immune resilience, particularly involving the TCF7 gene, protects against chronic inflammation, immunosenescence, and cell death.
Individuals in midlife with high immune resilience had a 69% lower mortality rate and a biological age advantage of up to 15 years. These findings spotlight immune resilience as a central factor in sustaining health and suggest that midlife is the optimal window for interventions to extend healthspan.