By National Institutes of Health –
Altering levels of certain molecules called transcription factors reversed some of the effects of aging in mice. The findings show the potential of targeting transcription factors to counter age-related illnesses.
The activity levels of many genes change as we age. Some of these changes contribute to age-related diseases. Slowing or reversing these changes, then, might help people stay healthier for longer.
Molecules called transcription factors influence how genes are expressed, or turned off and on. Changing levels of a single transcription factor could affect many other genes that drive aging and its health consequences. But only a few such transcription factors have been found thus far.
