Cellular senescence was a key factor.
by Josh Conway – Lifespan.io
Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest.
A common problem and a well-known diabetes drug
Long periods of disuse cause muscles to atrophy and accelerate the age-related muscle wasting known as sarcopenia [1]. Strength training is the accepted treatment for this problem, but with aging, it becomes less effective [2]. Therefore, more fundamental biological interventions are needed to combat atrophy-related frailty.
