by Felix Myhill – RegeMedNet
The recent identification of signaling pathways that determine bone stem cell fate could lead to new therapeutic targets to reverse age-linked skeletal impairment.
A recent study led by researchers from NYU Grossman School of Medicine (NY, USA) identified age-related changes in cell signaling pathways that are associated with a change in the proportions of different cell types that reduce skeletal integrity. They then pinpointed promising therapeutic targets, using information derived from the preclinical investigations, that could lay the groundwork for drugs that lessen age-associated bone degradation, such as in conditions like osteoporosis.
