By Linda Wang  – UCLA  –

The team will now seek FDA approval to open a clinical trial for the CAR-NKT cell therapy

UCLA researchers have developed a new type of immunotherapy called CAR-NKT cell therapy that, in patient-derived tumor samples, has been shown to be more effective at fighting ovarian cancer than conventional CAR-T cell therapy.

Unlike current cellular immunotherapies that require patient-specific manufacturing and can cost hundreds of thousands of dollars, CAR-NKT cells can be produced off-the-shelf, lowering costs to approximately $5,000 per dose.

The CAR-NKT platform shows promise for treating lung, brain and other solid tumors that have been challenging for CAR-T cell therapies to tackle.

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